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In the breast tissue, tamoxifen citrate is acting as a really powerful anti estrogen, and as a result of that is being very often used in the treatment of the hormone-responsive breast cancer condition in women. In fact, there are some instanced when tamoxifen is being used as a preventative measure as well, as is being used by women with an extremely high familial tendency for breast cancer.
But except for being a preventative medication and a drug helping with breast cancer in women, is also not an unheard fact that is being used by males. It is often being used by bodybuilder and athlete males as tamoxifen citrate is commonly used (as an off label use) to counter the side effects that are being caused by the elevated estrogens because of the use of some certain anabolic/ androgenic steroids.
In short: a person taking anabolic/ androgenic steroids is going to have high estrogen level and thanks to the excess of this hormone in the body, some side effects like water retention and gynecomastia will appear. Tamoxifen is taken during the steroid cycle in order to keep the estrogen levels low and avoid getting the side effects.
What is Tamoxifen (Nolvadex)?
About Tamoxifen Citrate
The biggest and main worry among the athletes and bodybuilding males is gynecomastia, or the very unsightly growth of female breast tissue in men. This can first be spotted by the appearance of a small swelling or a small lump under the nipple. In case this is going to be left untreated (leave it growing further), then this can very well develop into a quite large hard-tissue gynecomastia that pretty often may be an irreversible development without the surgical treatment.
In addition to that, the estrogen can also lead to an increase in the level of water that is being retained in the human body, therefore this is resulting in a pretty noticeable loss of definition as the muscles start to look smooth (sometimes even bloated) and that’s because of the retention of the subcutaneous fluid.
In addition to that, fat storage also may be seen increased since the estrogen levels are getting higher in men. As a matter of fact, the differences in the estrogen/ androgen ratio are one of the main reasons why women are normally having a higher body fat percentage and are having different fat distribution (hips, thighs), than men. When tamoxifen is taken during the risk of getting high estrogen levels, such risks are diminished. In men, usually high estrogen levels occur thanks to steroid use so men can avoid getting the side effects. In women, too high estrogen levels (mostly in breast tissues) can give breast cancer so this disease is either prevented or stopped by the use of tamoxifen.
How Does Tamoxifen Work?
Tamoxifen citrate is having the ability to increase the production of FSH (follicle stimulating hormone) as well as LH (luteinizing hormone). That is being accomplished by blocking the negative feedback inhibition that is being caused by estrogen at the hypothalamus that (via the actions of GnRH) encourages the release of the mentioned pituitary hormones. We could say that this is something pretty similar to the function of Clomid as well as cyclofenil, tamoxifen citrate can have a positive impact on the user’s serum testosterone level.
This “testosterone boost” effect is like an added bonus benefit when preparing to end a steroid cycle and that’s why is a preferred product by so many athletes out there. Due to the fact that it is widely known that anabolic/ androgenic steroids tend to suppress the endogenous natural testosterone production, tamoxifen citrate can help quite a lot to restore the needed balance in the hormone levels and give the little boost in testosterone production that an athlete needs after the steroid cycle. For this reason tamoxifen is most commonly used as part of a comprehensive post cycle recovery program (Post Cycle Recovery).
A pretty important note here is that pretty much like some other triphenylethylene compounds out there, tamoxifen citrate can work as an estrogen in the liver. Estrogenic action in the liver is essential in the regulation of the serum cholesterol, therefore this effect tends to support HDL (which is the good) cholesterol synthesis and is also helping to reduce the LDL (bad) cholesterol numbers.
Since the steroid-using bodybuilders are already dealing with quite some of the negative cardiovascular effects of those drugs, compounding the problem with aromatase inhibitors (AI’s) that in result are going to lower down the total serum estrogen levels – it may not always be the best option. Taking a drug that is blocking the process of gynecomastia, for example, while in the same time trying to support the improved cholesterol values, might be a much better idea in some cases.
It is also very important to take in consideration the fact that tamoxifen citrate is not a sufficient compound in order to stabilize serum cholesterol at healthy levels with the use of c-17alpha alkylated orals or high doses of steroids in general. The effect that it would have on the cholesterol values would very likely be one of degrees and it just cannot be relied upon in order to completely exclude the cardiovascular disease risk from the use of anabolic/ androgenic steroids.
What are the Side Effects of Tamoxifen?
Tamoxifen Citrate (Nolvadex) Side Effects
Some of the most common side effects that are being associated with the use of this product, tamoxifen citrate, is often including some of the following side effects: upset stomach; hair loss; lightheadedness; headache; hot flashes; edema; vaginal discharge; vaginal bleeding and vaginal itching.
There are also other side effects that were reported with the use of tamoxifen, however they are considered to be rarer, some of them that can be mentioned here are: visual disturbances; skin rash; endometriosis as well as some other endometrial changes; reduced platelet or white blood cell count; uterine fibroids; changes in the liver enzyme levels; increased triglyceride levels as well as deep vein thrombosis and pulmonary embolism. Plus, an increased incidence of endometrial cancer as well as uterine sarcoma has been reported too in the association with the tamoxifen citrate use.
Being an powerful hormonal changing medication, there’s a high chance that tamoxifen citrate (Nolvadex) would cause birth defects and therefore it shouldn’t be taken during pregnancy under any form.
How To Use Nolvadex (Tamoxifen)?
Tamoxifen Dosage / AdministrationTamoxifen citrate is a medication that most often is indicated for the use of:
- The treatment of metastatic breast cancer in both women and men
- Reducing the incidence of contralateral breast cancer (in the other breast) in the adjuvant setting
- Reducing the incidence of breast cancer in women at high risk for having breast cancer
- Reducing the incidence of invasive breast cancer in women with DCIS (Ductal Carcinoma in Situ) following breast surgery and radiation
- Adjuvant treatment of node-negative breast cancer following breast surgery and radiation
- Adjuvant treatment of node-positive breast cancer in postmenopausal women following breast surgery and radiation
In both women and men that are having metastatic breast cancer, a dose of anywhere between 10 mg to 20 mg (which is usually one or two tablets) is being administered twice per day (in the morning and in the evening) resulting a total dosage of either 20 mg to 40 mg per day. However, when this product is being used by men (as off label) in order to mitigate the estrogenic effects of the anabolic/ androgenic steroid use, then a daily dosage of 10 mg to 30 mg (which is usually 1 – 3 tablets) is usually used in the time that any offending steroids are being used, or as part of comprehensive post cycle hormone recovery program.
A pretty important note that should be mentioned here for the bodybuilders and athletes considering tamoxifen for their Post Cycle Hormone Recovery program is the fact that anti estrogen use may slightly reduce the gains that are made during a steroid cycle and that’s because a lot of androgenic/ anabolic steroids do seem to display their most powerful anabolic effects when are being accompanied by a sufficient level of estrogen (check for more information about Estrogen Aromatization).
This may very well be one of the reasons why those gains that are made with a strong aromatizable androgen like for example testosterone are normally more pronounced than those that are being achieved with anabolic steroids that aromatizes to a lower (or maybe absolutely no) degree.
Therefore, it is normally recommended to identify a specific need for tamoxifen citrate before starting to its use during a cycle. It is recommended that this product is used only if needed. That’s especially taking in consideration that in fact, it was discovered that many people find the use of the anti estrogen products unnecessary, and that’s in the time they are using some of the more problematic compounds like for example testosterone or methandrostenolone.
It very much depends on each personal needs individually because, in the same time there are people who do not need anti estrogens, there are other people out there that find they are having some pretty big problems with water retention and gynecomastia and that’s while they are having some of the milder (which means less estrogenic) drugs like for example Equipoise or Deca- Durabolin. For this reason we can easily conclude that the estrogenic response to the steroid use is very individual and it may very well be influenced by many different factors such as age and body fat percentage (the adipose tissue is a primary site of aromatization, that’s why body fat percentage may play an essential role here).
Where to Buy Nolvadex - Tamoxifen?
Why Buy Tamoxifen
Tamoxifen Citrate is a non-steroidal anti estrogenic drug. Medicinally it is most often being used either as a preventative medication for breast cancer that is hormone based or even to treat the already formed hormone based breast cancer in women. But being used off label by male bodybuilders and athletes, tamoxifen is very commonly used in order to fight off with the side effects that are the results of the elevated estrogens that in its place is the result of the use of certain anabolic / androgenic steroids.
It is not recommended to use tamoxifen unless you have elevated estrogen related issues however, if you do have these problems, then you can buy Tamoxifen (often known as Nolvadex) and make sure that you have made a really good purchase as it is a powerful drug that would help.