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There’s the belief that the fairly weak anabolic nature of this compound is indicating a tendency to block the androgen receptor in the muscle tissue and therefore is reducing the gains of some other more potent muscle building steroids, and that’s a belief that should likewise not be taken too seriously otherwise you might regret doing so. In fact, because of its extremely high affinity for plasma binding proteins like for example SHBG, Mesterolone actually may work to potentate the activity of some other steroids by displacing a higher percentage into a free, unbound state.
Among the athletes, Mesterolone is mainly being used in order to increase the androgen level during the time that the athlete is cutting down in the dieting phase where usually they are preparing for a show or content, and it is also often being used also as an anti estrogen because of its intrinsic ability to antagonize the aromatase enzyme. As said, the active substance in the Proviron (better known name of the steroid) is Mesterolone with chemical names: 1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one. The active life in the body of Mesterolone hormone is up to 12 hours but the detection time of this compound is 5 to 6 weeks.
In this article you should find a lot of important information include answers to the following questions:
What is Proviron (Mesterolone)?
How Long For Mesterolone Tablets to Work?
What is Mesterolone Used For?
What does Proviron Do?
How Dangerous is Mesterolone?
Estrogenic Side Effects of Mesterolone
Mesterolone is not being aromatized by the body, and therefore this steroid is not measurably estrogenic. All of this means that the high estrogen related side effects are not possible with the use of Mesterolone steroid. Since no estrogen related side effects can appear, the use of an anti estrogen while administering Mesterolone is useless because the product is not going to offer gynecomastia, water retention or any other estrogen related side effects.
In fact, Mesterolone is actually believed to work as an anti aromatase in the body which means that it is not only not going to offer any estrogen related side effects, but is also going to prevent or slow the conversion of the steroids into the estrogen. The result is going to be somewhat comparable to the very well known anti estrogen Arimidex, however the effects are still going to be less profound since Mesterolone, ultimately, is a steroid and not an anti estrogen. This is not something unheard of as the anti estrogenic properties of Mesterolone are not unique because there’s a number of some other steroids which have proven to have similar activity.
Dihydrotestosterone and Masteron (2-methyl-dihydrotestosterone), for example, have been successfully used as therapies for gynecomastia and for breast cancer because of their strong androgenic and potentially anti estrogenic effect. In addition to that, it also has been suggested the fact that nandrolone may even lower aromatase the activity in peripheral tissues, the area where it is being more resistant to estrogen conversion (the most active site of the nandrolone aromatization seems to be the liver).
The anti estrogenic activities of all of those substances are presumably being caused by their ability to compete with some other substrates for the binding to the aromatase enzyme. With the aromatase enzyme that is being bound to the steroid, and yet is being unable to alter it, pretty much something like an inhibiting effect is being achieved as it is being temporarily blocked from interacting with some other hormones.
Mesterolone Androgenic Side Effects
Mesterolone is being categorized as an androgenic steroids instead of anabolic steroids and that’s because it has much more androgenic activity than anabolic activity. With this being said, it is pretty obvious that the steroid is indeed having some possible androgenic side effects. in fact, the androgenic side effects are pretty common with this compound, and that’s especially holding true for the higher doses.
This is including bouts of oily skin, acne, body/ facial hair growth but whether or not you are going to get these side effects is highly depending on your genetics. In addition to that, the anabolic/ androgenic steroids (especially androgenic steroids like Mesterolone) also may aggravate/ fasten the male pattern hair loss condition. If you are not genetically predisposed to this side effect or if that’s not a concern for you, then this won’t be a problematic side effect.
Plus to all of this, women are also being warned of the potential virilizing effects of the anabolic/ androgenic steroids. These virilizing side effects are including a deepening of the voice, clitoral enlargement, menstrual irregularities, facial hair growth as well as changes in the skin texture. You should know that in case these side effects do appear, you should discontinue the steroid use at their onset because this way the side effects would most likely disappear very soon without any problems. However, in case the symptoms are being ignored and you continue using the steroid further, there’s a high chance that the side effects would be permanent and irreversible.
Plus to everything mentioned, the 5 alpha reductase enzyme is not metabolizing Mesterolone, this means that its relative androgenicity is not going to be affected by the 5 alpha reductase products like for example Finasteride or Dutasteride.
Mesterolone Hepatotoxic Side Effects
Mesterolone is a steroid that is taken in form of tablets by mouth and yet, is not a c17 alpha alkylated product, therefore this substance should not offer absolutely any stress to the liver.
This product is not known to offer any hepatotoxic effects and with all of this being said it means that liver toxicity is very unlikely to occur.
Mesterolone Cardiovascular Side Effects
Any anabolic or androgenic steroids can and in most cases they will have deleterious effects on the serum cholesterol. Depending on different factors, the effects can be small, but they can be extremely bad. The effects on the cholesterol is including the tendency to reduce the HDL (good cholesterol) numbers and in the same time to increase the LDL (bad cholesterol) numbers and this can change the HDL to LDL balance into a way that is going to greatly favor the risks of getting arteriosclerosis. The impact of the steroid is depending on a few different things. For example, the impact of the steroids on the serum lipids depends on the route of administration (oral or injectable), is very highly dependent on the dosage, on the type of steroid (either aromatizable or non aromatizable) as well as on the level of the resistance to the hepatic metabolism.
Talking about this product specifically – Mesterolone is an oral steroid and is a non aromatizable androgen, and these are the main reasons why it is expected to have a pretty noticeable negative effect on the lipids. There are some studies done which are proving the fact that using 100 mg of Mesterolone a day by the hypogonadal men for approximately half a year (6 months) it has proven the fact that a significant increase in the total cholesterol (around 18.8%) and in the LDL (bad) cholesterol values (by around 65.2%) in addition to that it has been accompanied by a very significant suppression in the HDL cholesterol values ( - 35.7 %). Remember that Mesterolone should not be taken when the cardiovascular risk factors are precluding the use of some other oral steroids.
During the administration with any anabolic/ androgenic steroid – it is essential to maintain a cholesterol friendly lifestyle as this can greatly help to reduce the potential cardiovascular/ cholesterol issues. In order to reduce the cardiovascular strain, is strongly advised to keep an active cardiovascular exercise program. Plus to this, a diet would be very important as well. The individual should have a diet where the intake of the saturated fats, simple sugars/ carbohydrates and cholesterol should be minimized or completely avoided in case it is possible. In addition to that, a cholesterol friendly diet should include lots of omega fatty acids, therefore supplementing with daily fish oils (at least 4 grams a day) is greatly recommended.
One last thing. adding a natural cholesterol/ antioxidant formula like for example Lipid Stabil or a product that is having some comparable ingredients is very recommended as well. All of these steps should be kept during the entire active administration with Mesterolone or whatever other steroid. But before everything – if you already have some cholesterol/ cardiovascular issues – do not use Mesterolone.
Mesterolone Testosterone Suppression Side Effects
Mesterolone is a steroid that is offering a very weak suppressive effect on the gonadotropins and serum testosterone. While it does offer some suppressive effect on the testosterone when the product is being taken in doses high enough to be considered effective – it doesn’t offer by far as suppressive effects as other steroids out there.
For example, there are some studies which are proven that when the product is being given in some moderate doses (like for example 150 mg per day or less), the significant suppression of the testosterone levels does not occur.574 However, the suppression does occur to some extent and in addition to that, there are other studies which used higher doses (300 mg per day and over it) which proven that the agent has significantly suppressed the serum testosterone at this dosage. Plus, the above side effects are not being inclusive here.
How To Take Proviron (Mesterolone)?
Mesterolone Administration for Men
This product is mostly offered clinically to people who are having androgen insufficiency and so, in order to treat androgen insufficiency condition, Mesterolone is commonly being prescribed in a dose of 1 tablet (25 mg) 3 times a day (which means a total dose per day of 75 mg) at the initiation of the therapy. However, then later the drug is being continued at a lower maintenance dose, which is commonly consisting of using 1 tablet (25 mg) one to 2 times a day (25 mg to 50 mg daily).
These are considered moderate doses which can be helpful for such condition and plus – most men are tolerating such doses without any issues. Plus to this, some similar doses are being used in order to support male fertility either but usually the steroid is being given alongside with some other fertility drugs like for example the injectable FSH.
The usual dosage among the male athletes that are using it for performance and/ or physique enhancing purposes is anywhere between 50 mg and 150 mg of Mesterolone (Proviron) per day which means that they are using anywhere between 2 to 6 tablets of 25 mg daily. Doses higher than 150 mg per day are not uncommon, however, generally such a practice is not recommended because this is getting the risks of side effects much higher. This steroid, is usually being used in cycles of anywhere between 6 to 12 weeks in length and usually, that’s considered to be an enough period of the time to start seeing the benefits using this steroid.
There are a lot of bodybuilders who are offering a big favor to the use of Mesterolone during the dieting phases or during the contest preparation and that’s most likely during the time when some low estrogen levels and high androgen levels are most likely desirable. It is said that this is being especially beneficial when the anabolics like for example Primobolan, Anavar or Winstrol are being taken alone during the cycle and that’s because the androgenic activity of those steroids is relatively low.
Taken with a high androgen rated product like Mesterolone would greatly help. The Mesterolone steroid can be used with great effectiveness here in order to adjust the androgen to estrogen ratio upwards, which is going to offer about an increase in the hardness and in the density of the muscles, plus is going to help with the libido and also general sense of well being, and also would be helpful in increasing the rate of burning the body fat either. plus to everything, the product is also being usually being used (in a pretty much same dosage range) in order to prevent gynecomastia when some other aromatizable steroids are being administered, and very often that’s being done alongside with around 10 to 20 mg per day of Nolvadex either.
Mesterolone Administration for Women
Mesterolone is a steroid that is considered to be fairly mild in terms of side effects and yet – the compound is not being approved for use in women and that’s because of the strong virilizing symptoms it may offer. This compound is not being recommended for women for any reasons including physique or performance enhancing purposes. As said, this is an androgenic steroid which means that it has a strong androgenic nature and a big tendency to offer virilizing side effects even in moderate doses for most women trying to use it.
Nonetheless, there are still some women who took the change and they favor the drug. They find that a single tablet of 25 mg is going to be enough to efficiently shift the hormone balance in the body, as they report that this dosage doesn’t produce bad virilizing effects and it is greatly going to impact the look of the definition to their physique. However, this greatly depends on genetics as well. Remember that the intake is commonly being limited to no longer than 4 or maximum 5 weeks in such a situation and that’s in the attempt to minimize the risks of getting the virilizing effects. It is extremely important to stop using the steroid as soon as you get the first symptom in order to avoid having them permanently.
Plus to everything, one tablet being used alongside with the 10 or 20 mg of Nolvadex is reportedly to be even more efficient for the muscle hardening effects, as this mixture is going to create an environment here where it is allowing the body to have a much more tendency to burn off the extra body fat, and that’s especially in those females that are having trouble areas like for example the hips and thighs. Nonetheless, remember that Mesterolone is not recommended for female use in the first place and that’s why extreme caution should be taken while using it. The use should be as much limited as it is possible and with doses that are as limited as possible.
Where To Buy Proviron (Mesterolone)?
Why Buy Mesterolone
By purchasing Mesterolone from our website you are going to be happy with the results you are going to get from it as it is considered to be a steroid much milder compared to other steroids, especially in some side effects like for example testosterone suppression. That’s because the high quality drugs and low prices of drugs would ensure that they would do what they are supposed to.
Mesterolone is an androgenic steroid and this is one main reason why is not recommended for women’s use, although there are some women who use it with some success. But this should be done with great care. It has strong anti estrogenic properties and it is used by lots of athletes for many reasons like burning fat, enhancing muscularity and definition.