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One very important fact to mention here is that this drug they are prohibited to be used in the combination with Tamoxifen because this stuff is believed that it can decrease their effect quite significantly.
The chemical name of this substance is 4,4′-((1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile with the formula: C17H11N5. It is important to know that the half life (the period in which half of the substance is going to be flushed out of your body) is 2 to 4 days but the detection time for this substance is 2 weeks.
What is Letrozole (Femara)? What is femara used for?
Letrozole (that is mostly known as its brand name – Femara) is an aromatase inhibitor that was designed to treat the hormonally responsive breast cancer after surgery in women, but this produt got its name in the bodybuilding community as well. Being an aromatase inhibitor, the product can do a great job in controlling the estrogen levels which are often elevated during the administration with a steroid.
With this being said, the steroid user is able to control estrogen levels so it can do a great job in making the user avoid such side effects as: water retention, gynecomastia or high blood pressure due to water retention.
How does Femara (Letrozole) work?
So well, in order to understand the mechanism of this product’s action it is important to clarify one of the main reason for the breast cancer appearing. There are specialists which claim that among the postmenopausal women, the main reason for the breast cancer is the estrogen which is circulating in the blood and is causing the occurring of the malignant tumors or their growth increasing. Those estrogens are being produced in the adrenal glands of the female organism.
As said, Letrozole is a substance, an oral drug that is aimed at stopping of those estrogens production or better said – the drug is inhibiting that enzyme which is responsible for their production. This is the main reason why this product is being classified into the type of “anti estrogen” medications. Letrozole is blocking the production of the estrognes in a way by competitive, reversible binding to the heme of its cytochrome P450 unit. Letrozole is selectively inhibiting the gonadal steroidogenesis, however, it still has no significant effect on glucocorticoid synthesis or adrenal mineralocorticoid.
Letrozole (Femara) Side Effects
The possible side effects of Letrozole while administering with the drug include: pain in the chest, headaches, vomiting, nausea, digestive issues (constipation or diarrhea) as well as tiredness. It is important to know that this is a drug that is decreasing the density of bones in your body and this means that you need to regularly check the health condition (especially of your bones) while administering this product. By not doing so and continuing to use the product, you risk to get osteoporosis.
Another thing to mention here is that Letrozole is not being recommended to people who are suffering from high level of cholesterol. That’s because Letrozole can interfere with your cholesterol levels and it may increase it, therefore this can lead to some serious health issues.
It is important to keep in mind that Letrozole, generally, is a pretty well tolerated drug, however, only if you’re taking the normal dosage. By not overdoing it – you are going to tolerate it pretty well.
Femara (Letrozole) Dosage / Administration
How To Take Letrozole?
It is important to keep in mind that the side effects of this product (their intensity and frequency) are directly related to its dosage. This means that the higher the dosage is – the higher the risk of getting side effects gets, and also their intensity and frequency. That’s why, in order to reduce the probability of side effects occurring you need to stick to the recommended dosage of the drug.
The absorption of this substance is not being affected by food, so it doesn’t matter if you’re taking it with or without food. The product is usually given at the dosage of 2.5 mg a day for females treating breast cancer.
However, the dosage protocol of Letrozole for bodybuilders is much lower. For example, bodybuilders are usually taking a dosage of 0.5 mg to maximum 1 mg a day as it is considered that this level is going to be enough to deal with the high estrogen related side effects. Doses as high as 2.5 mg are given only to those men who are having huge estrogen issues, for example, to those who are developing visible gynecomastia (man boobs).
What happens when you stop taking Letrozole?
Letrozole is a product that generally do not need to be stopped taking it gradually. This is why, this product can be stopped abruptly.
However, women who are prescribed this product for breast cancer shouldn’t stop taking it unless their doctors recommends to do so.
Where to Purchase Femara (Letrozole)?
Why Buy Letrozole?
Letrozole is an anti estrogen product categorized as an Aromatase Inhibitor (AI) which is generally used to treat infertility in women, hormonally induced breast cancer as well as is very widely used by bodybuilders.
This product is going to do a great job in controlling the estrogen levels as is one of the most effective products in doing so. On our website, you’re going to find the best products containing Letrozole for controlling the estrogen issues.